Evaluation of epitopes specificity of antibodies to thyroid peroxidase in autoimmune thyroid disorders

Thyroid peroxidase antibodies in children with autoimmune thyroiditis.

AIMS To compare the prevalence of thyroid peroxidase antibodies in 25 children with autoimmune thyroid disorders and in 41 children and young adults with type 1 diabetes, and to test the prevalence of thyrotropin receptor antibodies. METHODS Two commercially available radioimmunoassays for antibodies to thyroid peroxidase, a commercially available agglutination test of particles coated with t...

prevalence of autoantibodies to thyroid peroxidase and autoimmune thyroid disease in girls with turner’s syndrome

patients with turner’s syndrome (ts) are at an increased risk of developing autoimmune thyroid disease (atd). the aim of this study was to determine the frequency of anti-thyroid peroxidase (anti-tpo) antibodies and atd in children and adolescent girls with ts. it also assessed the influence of karyotype on the development of thyroid disease. sixty eight patients with ts were compared with 68 a...

Autoimmune Thyroid Disorders

Thyroid autoimmunity, as reflected by the presence in serum of autoantibodies directed against the thyroid autoantigens thyroglobulin (Tg) and thyroid peroxidase (TPO), is present in >10% of the US population over 12 years of age [1] and is the most common cause of endocrine dysfunction in iodine-sufficient populations [2]. The underlying mechanism is a failure of T-cell tolerance leading to ly...

[Antimicrosomal antibodies and thyroid peroxidase antibodies (TPOAb)].

Autoimmune Thyroid Disorders

Purpose of Review. Studies have been published in the field of autoimmune thyroid diseases since January 2005. The review is organized into areas of etiology, autoimmune features, autoantibodies, mechanism of thyroid cell injury, B-cell responses, and T-cell responses. Also it reviews the diagnosis and the relationship between autoimmune thyroid disease, neoplasm, and kidney disorders. Recent F...